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Microprocessor Tablet Dissolution Test Apparatus – EI-DVI Make:
The Microprocessor Dissolution Test Apparatus, offered under the EI-DVI brand, is a solid state instrument specifically designed for pharmaceutical quality control and research and development (R&D) applications. This sophisticated apparatus determines the release rate of the active drug ingredient contained within pharmaceutical formulations, such as tablets or capsules.
Manufactured by ESICO INTERNATIONAL, an ISO 9001:2008 Certified Company, this instrument utilizes the latest microprocessor technology and advanced engineering techniques to ensure enhanced accuracy and high reproducibility of test results.
Overview and Compliance:
The primary function of the dissolution tester is to evaluate the adequate bio-availability of pharmaceutical dosage forms. By determining compliance with dissolution requirements, the apparatus provides essential information needed to formulate and develop therapeutically optimum dosage forms. The unit is designed to meet strict pharmacopeia guidelines, performing tests strictly as per IP (Indian Pharmacopoeia) and USP (United States Pharmacopeia) specifications.
Control and User Interface:
The instrument is designed with user-friendly prompts that guide the operator throughout the entire measurement process. The system features a clear display and a robust keyboard interface for easy operation:
• Display: Models 2912 and 2914 feature a 20 x 4 line alphanumeric LCD display with backlit illumination.
• Keypad: Data input is managed via 19 soft touch membrane type keys.
• Direct Control: Independent keys are provided on the front panel allowing the user to easily start or stop the stirrer movement or control the displacement of the platform at any time.
• Status Indicators: The apparatus includes four LEDs for general status indications, with three specifically dedicated to test status (Run, Alarm, End), and one LED to indicate the heater ON/OFF status.
• Memory: The system is capable of storing 20 different test setups in both routine and sustain modes.
• Printing Capability: Provision is available for the attachment of a dot-matrix printer utilizing a standard centronics parallel port interface.
Mechanical and Temperature Control Features:
The dissolution tester is equipped with precise control systems for stirring and heating, crucial for meeting stringent USP/IP standards.
The dissolution vessel is typically a 1000 ml jar, supplied along with a stirrer pedal and basket, made of stainless steel. The unit may come in various configurations, including the Deluxe EI-DVI 1912 Single Basket, the Microprocessor Based 6 Bucket (Model 1916), 8 Bucket (Model 1918), or large capacity units like the 12 and 14 station models (2912 and 2914, respectively).
Temperature control is managed by a microprocessor using a PT100 or Semiconductor sensor.
Technical Specifications (Model 2914):
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Parameter
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Specification / Detail
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Model Variations
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14 stations (Model 2914), 12 stations (Model 2912)
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Stirrer Speed
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25 to 200 RPM
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Stirrer Accuracy
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± 1 RPM
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Stirrer Resolution
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1 RPM
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Temperature Range
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30 to 50 °C
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Temperature Accuracy
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± 0.2 °C
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Temperature Control
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Microprocessor based using PT100/Semiconductor sensor (as per IP/USP)
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Display Type
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20 x 4 line alphanumeric LCD with backlit
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Keyboard
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19 soft touch membrane type keys
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Setup Data Storage
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20 different test setups (routine and sustain modes)
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Heater Power
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1900 W
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Reaction Vessel Capacity
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1000 ml
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Power Requirement
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230 V ± 10%, 50 Hz. AC
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Standard Accessories
The Microprocessor Dissolution Test Apparatus generally includes the following standard accessories to ensure readiness for immediate operation:
• Main Unit including the acrylic tank, rectangular cover plate, water bath temperature sensor (T1), two heaters, and circulating pump.
• External temperature sensor (T2) for the vessel.
• Reaction vessels (1000 ml capacity).
• Round acrylic cover plate equipped with a hole and a large slit.
• Stainless Steel (S.S.) Paddles and S.S. Wire mesh baskets.
• S.S. Pillars (4 Nos.) used for holding the rectangular cover plate.
• Glass pipettes (3 Nos.).
• Rubber bellow.
• Thermometer and Thermometer Holders.
• Level Screws (10 Nos.).
• Spare Clips for Fixing the Vessel Cover.
• Spare Fuse (10 Amps, 2 Nos.).
• Circulating pump main lead.
• Allen Key 4 mm.
• Instruction manual and dust cover.
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